Products & Services

  • Biotech

    Isolator applications include models for the derivation, housing and transfer of a range of laboratory animal species with environments for germ free, specific pathogen free, CL3 and CL4 biohazard containment.
  • Phamaceutical

    Isolator applications include sterility test, sterile process, aseptic process, biohazard, toxic and cytotoxic containment.
  • Customised

    Although we have an extensive range of standard isolator designs, we specialise in providing customised versions of our standard models to meet individual client requirements.
  • Bespoke

    For applications where a standard system will not provide an ideal solution, we offer a bespoke design and build service to provide the client with a product to meet their exacting requirements.

Bell Isolation Systems are market leaders in the design, manufacture, installation and maintenance of high quality flexible film and rigid body isolator systems and associated products for Biotech and Pharmaceutical applications.

Our Products

Biotech Isolator Systems

Isolator applications include models for the derivation, housing and transfer of a range of laboratory animal species with environments for germ free, specific pathogen free, CL3 and CL4 biohazard containment.

The BioFlex® B10 Flexible Film Transfer/Service Isolator is a multi-functional design which will provide a sterile positive pressure or contained negative pressure environment suitable for laboratory animals. The B10 Isolator can be used to transfer laboratory animal cages, equipment or materials between isolators.  To house small numbers of laboratory animals, an extension for storage, procedures or as a disinfection enclosure. Operator access to the internal workspace is through gloved sleeves fitted to the front and back canopy panels. 

 

Options

Collapsible Cage Racking, Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings, Digital Thermohygrometer, Docking Flange

 

Dimensions

Overall

1200mm (L)

750mm (D)

1900mm (H)

 

Cage Capacity

NKP Type M1/M2

12

Tecniplast Eurostandard Type 1264C

9

Tecniplast Eurostandard Type 1144B

12

Tecniplast Eurostandard Type 1284L

9

Tecniplast Eurostandard Type 1290D

2

BioFlex® B20 Surgical/Procedures/Hysterectomy Isolator has been developed for use with the BioFlex® Series Isolators for hysterectomy derivation or surgical procedures on small rodents.

 

Options

Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Electrical Sockets, Illumination, H2O2 Couplings

 

Dimensions

Overall

1685mm (L)

785mm (D)

1775mm (H)

The Surgical/Procedures Isolator is designed in two standard sizes and can also be used as a laboratory isolator for sterile or biohazardous procedures including autopsy work.  Operator access to the internal workspace is through gloved sleeves fitted to the front and rear canopy panels. 

 

Options

Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings

 

Dimensions (compact version)

Overall

1200mm (L)

700mm (D)

1850mm (H)

 

Dimensions (standard version)

Overall

1550mm (L)

900mm (D)

1900mm (H)

Two Glove Compact Flexible Film Trolley Isolator, designed to provide a sterile positive pressure or contained negative pressure environment for housing small rodents in cages.  Operator access to the internal workspace is through gloved sleeves fitted to the front and back canopy panels. 

 

Options

Collapsible Cage Racking, Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings, Digital Thermohygrometer, Docking Flange.

 

Dimensions

Overall

1600mm (L)

900mm (D)

1900mm (H)

 

Cage Capacity

NKP Type M1/M2

20

Tecniplast Eurostandard Type 1264C

15

Tecniplast Eurostandard Type 1144B

20

Tecniplast Eurostandard Type 1284L

15

Tecniplast Eurostandard Type 1290D

4

Tecniplast Eurostandard Type 1291H

4

Four Glove Medium Size Flexible Film Trolley Isolator, designed to provide a sterile positive pressure or contained negative pressure environment for housing small rodents in cages.  Operator access to the internal workspace is through gloved sleeves fitted to the front and back canopy panels.

 

Options

Collapsible Cage Racking, Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings, Digital Thermohygrometer, Docking Flange

 

Dimensions

Overall

1900mm (L)

900mm (D)

1900mm (H)

 

Cage Capacity

NKP Type M1/M2

30

NKP Type RB3

6

Tecniplast Eurostandard Type 1264C

25

Tecniplast Eurostandard Type 1144B

35

Tecniplast Eurostandard Type 1284L

25

Tecniplast Eurostandard Type 1290D

8

Tecniplast Eurostandard Type 1291H

8

Four Glove Medium Size Flexible Film Trolley Isolator designed to provide a sterile positive pressure or contained negative pressure environment for housing small rodents in cages. The B65 isolator dimensions have additional depth for housing longer cages. Operator access to the internal workspace is through gloved sleeves fitted to the front and back canopy panels.

 

Options

Collapsible Cage Racking, Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings, Digital Thermohygrometer, Docking Flange.

 

Dimensions

Overall

1900mm (L)

1000mm (D)

1900mm (H)

 

Cage Capacity

NKP Type M1/M2

30

NKP Type RB3

9

Tecniplast Eurostandard Type 1264C

25

Tecniplast Eurostandard Type 1144B

35

Tecniplast Eurostandard Type 1284L

25

Tecniplast Eurostandard Type 1290D

16

Tecniplast Eurostandard Type 1291H

16

The Four Glove Large Size Flexible Film Trolley Isolator designed to provide a sterile positive pressure or contained negative pressure environment for housing a large capacity of small rodents in cages.  Operator access to the internal workspace is through gloved sleeves fitted to the front and back canopy panels.

 

Options

Collapsible Cage Racking, Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings, Digital Thermohygrometer, Docking Flange.

 

Dimensions

Overall

2400mm (L)

900mm (D)

1900mm (H)

 

Cage Capacity

NKP Type M1/M2

50

NKP Type RB3

12

Tecniplast Eurostandard Type 1264C

40

Tecniplast Eurostandard Type 1144B

55

Tecniplast Eurostandard Type 1284L

40

Tecniplast Eurostandard Type 1290D

12

Tecniplast Eurostandard Type 1291H

12

The Four Glove Large Size Flexible Film Trolley Isolator designed to provide a sterile positive pressure or contained negative pressure environment for housing a large capacity of small rodents in cages.  Operator access to the internal workspace is through four gloved sleeves fitted to the front rear canopy panels.

 

Options

Collapsible Cage Racking, Stainless Steel Worktray, Electronic Height Adjustable Base Trolley, Small Samples Port, Ring Mounted Sleeves, Telescopic Easy Change Cuff System, Exhaust Ventilation Ducting, Additional In Series Safe to Change HEPA Filter, Automatic Battery Back Up System, Electrical Sockets, Illumination, H2O2 Couplings, Digital Thermohygrometer, Docking Flange.

 

Dimensions

Overall

2400mm (L)

900mm (D)

1900mm (H)

 

Cage Capacity

NKP Type M1/M2

50

NKP Type RB3

12

Tecniplast Eurostandard Type 1264C

40

Tecniplast Eurostandard Type 1144B

55

Tecniplast Eurostandard Type 1284L

40

Tecniplast Eurostandard Type 1290D

12

Tecniplast Eurostandard Type 1291H

12

The Poultry Isolator is a mobile rigid body isolator system with positive or negative pressure operation, designed specifically for housing poultry species.  The design allows birds to be housed without caging on sectioned floor grids or housed directly on the floor using woodchips or a suitable absorbent bedding material.  When operated in the positive pressure mode the isolator can be used to provide a sterile environment suitable for housing and maintaining SPF or germ-free birds.  When operated in the negative pressure mode the isolator can be used to maintain an ACDP Category 3/SAPO 4 biohazard contained environment suitable for housing infected birds with category 3 pathogens.

 

Dimensions (B50)

Overall

2545mm (L)

835mm (D)

1740mm (H)

 

Capacity

Species & Weight (grams)

Min Area – One Bird (cm2)

Qty

Min Area – Three Birds (cm2/bird)

Qty

Chickens 100-300

250

50

150

84

Chickens 300-600

500

25

300

42

Chickens 600-1200

1000

12

450

28

Chickens 1200-1800

1200

10

550

22

Chickens 1800-2400

1400

9

650

19

Adult Males >2400

1800

7

1000

12

 

Dimensions (B55)

Overall

2730mm (L)

1130mm (D)

1740mm (H)

 

Capacity

Species & Weight (grams)

Min Area – One Bird (cm2)

Qty

Min Area – Three Birds (cm2/bird)

Qty

Chickens 100-300

250

50

150

134

Chickens 300-600

500

25

300

67

Chickens 600-1200

1000

12

450

44

Chickens 1200-1800

1200

10

550

36

Chickens 1800-2400

1400

9

650

31

Adult Males >2400

1800

7

1000

20

Where our standard models do not fully meet your requirements, we have a wealth of experience in the design and manufacture of bespoke isolators and associated equipment.

 

We will meet with you to discuss the process in detail, listen and learn what you are hoping to achieve.  We will then use our experience and skills to develop a solution which can be taken from concept to project realisation using the latest 3D CAD design software in accordance with our ISO9001 Quality Management System.  We will also discuss the preferred method of sterilisation/ decontamination and ensure the isolator materials are compatible and connection systems are suitable for the chosen method.

 

The isolator is then validated to ensure all of the relevant regulatory standards and requirements including ISO 14644-1 Cleanroom & Associated Controlled Environment, EU cGMP Guidelines are fully met and an installation, commissioning and validation programme including FAT, SAT DQ, IQ, OQ and PQ is developed and agreed.

Pharmaceutical Isolator Systems

 Isolator applications include sterility test, sterile process, aseptic process, biohazard, toxic and cytotoxic containment.

The BioFlex® B10 Flexible Film Transfer/Service Isolator is a multi-functional design which will provide as a minimum EU GMP Grade A clean air working environment for sterile positive pressure or contained negative pressure pharmaceutical applications.    The B10 Isolator can be used for a variety of procedures including transferring product, equipment or materials between isolators or as an extension to a larger isolator for storage.  Operator access to the internal workspace is through gloved sleeves fitted to the front and back canopy panels. 

 

Dimensions

Overall

1200mm (L)

750mm (D)

1900mm (H)

The BioFlex® B30 Flexible Film Pharmaceutical Process Isolator operates at positive or negative pressure, providing an EU Grade A environment for a variety of sterile or contained pharmaceutical processes including sterile or aseptic processing, sterility test, handling and processing cytotoxic drugs or compounds.

 

Operator access to the internal workspace is through strategically located gloved sleeves sealed to the front and back canopy panels. 

 

Dimensions

Overall

1242mm (L)

990mm (D)

1954mm (H)

BioFlex® B90 Flexible Film Glove Isolator, designed to provide and maintain a secure sterile environment for sterility testing according to pharmacopoeial or client methods, using a Sterility Test pump integrated into the worktray.

 

The Isolator design and dimensions will allow a variety of equipment associated with the sterility testing procedures to be housed and operated within the sterile workspace with space remaining available for additional equipment and materials to be added. 

 

Dimensions

Overall

2440mm (L)

850mm (D)

1950mm (H)

The BioFlex® B100 Flexible Film Half-Suit Containment Isolator system is designed to operate at negative pressure only, providing a secure contained environment for working with materials infected with pathogens specified as up to SAPO4/ACDP3.

The isolator can house a variety of equipment required for the processes including an incubator, refrigerator and a centrifuge.  The isolator can also be fitted with cage racking to house groups of rodents in cages.

The main operator access is provided through a single flexible PVC half-suit with an independent HEPA filtered air supply system.         

 

Dimensions

Overall

2450mm (L)

2000mm (D)

2540mm (H)

BioFlex® B100 Positive Pressure Flexible Film Half-Suit Isolator designed to provide a minimum EU GMP Grade A environment for Sterile Processing or Sterility Testing applications.  The Half-Suit Isolator has an automatic microprocessor control system, Peracetic Acid vapour or H2O2 gassable transfer port and integral sterility test media pump.

The main operator access is provided through a single flexible PVC half-suit with an independent HEPA filtered air supply system.

 

Dimensions

Overall

2450mm (L)

2000mm (D)

2534mm (H)

Where our standard models do not fully meet your requirements, we have a wealth of experience in the design and manufacture of bespoke isolators and associated equipment.

 

We will meet with you to discuss the process in detail, listen and learn what you are hoping to achieve.  We will then use our experience and skills to develop a solution which can be taken from concept to project realisation using the latest 3D CAD design software in accordance with our ISO9001 Quality Management System.  We will also discuss the preferred method of sterilisation/ decontamination and ensure the isolator materials are compatible and connection systems are suitable for the chosen method.

 

The isolator is then validated to ensure all of the relevant regulatory standards and requirements including ISO 14644-1 Cleanroom & Associated Controlled Environment, EU cGMP Guidelines are fully met and an installation, commissioning and validation programme including FAT, SAT DQ, IQ, OQ and PQ is developed and agreed.

Maintenance and Flexible PVC Product Replacement

Spares 

We offer a full range of consumables and spares specific to your standard, customised or bespoke product.  A comprehensive list of spares and consumables can be found in the operating guide provided or can be obtained either from your local distributor or direct from Bell Isolation Systems Ltd.

 

Flexible PVC Products 

At Bell Isolation Systems, the flexible film components are manufactured in-house. In addition to manufacturing components for our own products we manufacture a wide range of components for other makes of isolator.  We also offer the same bespoke design and manufacturing service using our 3D Computer Aided Design (CAD) software. 

 

Typical flexible film products include, replacement sleeves, canopies, transfer and docking sleeves, spray-bags and isolator half-suits.     

 

The materials used are of the highest quality, optical clarity and in addition to our standard UV stabilised flexible PVC materials, we also manufacture products from anti-static PVC. 

 

Maintenance 

Our after sales support ensures that products are maintained ‘in the field’ by providing comprehensive maintenance and service agreements, securing optimum equipment reliability.

 

Once the warranty has expired, we offer bi-annual, annual or multi-year service contracts to ensure the equipment continues to operate safely and reliably.

 

For installations outwith the UK, this service can be provided by our UK based engineers or through one of our agents.